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[Postoperative radiotherapy of breast cancer and cardiotoxicity]. / Posztoperatív emlobesugárzás és cardiotoxicitas.
Nagykálnai, Tamás; Nagy, A Csaba; Landherr, László.
Affiliation
  • Nagykálnai T; XV. kerületi Szakrendelo Onkológia Budapest.
  • Nagy AC; Uzsoki utcai Kórház I. Belgyógyászat Budapest.
  • Landherr L; Uzsoki utcai Kórház Onkoradiológiai Központ Budapest.
Orv Hetil ; 155(23): 897-902, 2014 Jun 08.
Article in Hu | MEDLINE | ID: mdl-24880968
Cardiac complications may present a particular problem following radiation treatment applied to the mediastinum and thoracic wall (and especially to the left breast). Exposure of the heart during radiotherapy increases the risk of ischemic heart disease occurring generally years after the treatment. The incidence of radiation cardiotoxicity depends on various factors related to oncological therapies and the patient (details of radiotherapy, age, gender, comorbidities, smoking habits, etc.). Until recently the majority of clinical studies reported increased cardiac morbidity in patients receiving radiation treatment of the chest wall and the breast. Due to modern methods, however, postoperative chest wall and left breast irradiation is much safer today than previously. In order to avoid cardiotoxicity, adherence to clinical practice guidelines for chemo- and targeted therapy of breast cancer, use of the most advanced irradiation procedures, regular monitoring of patients, and close cooperation between cardiologists and oncologists are all recommended.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Injuries / Breast Neoplasms / Myocardial Ischemia / Radiotherapy, Adjuvant / Heart Type of study: Etiology_studies / Guideline Limits: Female / Humans Language: Hu Journal: Orv Hetil Year: 2014 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Injuries / Breast Neoplasms / Myocardial Ischemia / Radiotherapy, Adjuvant / Heart Type of study: Etiology_studies / Guideline Limits: Female / Humans Language: Hu Journal: Orv Hetil Year: 2014 Type: Article