Changes in the treatment of Enterococcus faecalis infective endocarditis in Spain in the last 15 years: from ampicillin plus gentamicin to ampicillin plus ceftriaxone.

Pericas, J M; Cervera, C; del Rio, A; Moreno, A; Garcia de la Maria, C; Almela, M; Falces, C; Ninot, S; Castañeda, X; Armero, Y; Soy, D; Gatell, J M; Marco, F; Mestres, C A; Miro, J M

Changes in the treatment of Enterococcus faecalis infective endocarditis in Spain in the last 15 years: from ampicillin plus gentamicin to ampicillin plus ceftriaxone.

Pericas, J M; Cervera, C; del Rio, A; Moreno, A; Garcia de la Maria, C; Almela, M; Falces, C; Ninot, S; Castañeda, X; Armero, Y; Soy, D; Gatell, J M; Marco, F; Mestres, C A; Miro, J M.

Affiliation

Pericas JM; Infectious Diseases Service, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

Clin Microbiol Infect ; 20(12): O1075-83, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25040215

Subject(s)

Ampicillin/therapeutic use; Anti-Bacterial Agents/therapeutic use; Ceftriaxone/therapeutic use; Endocarditis/drug therapy; Enterococcus faecalis/isolation & purification; Gentamicins/therapeutic use; Gram-Positive Bacterial Infections/drug therapy; Aged; Aged, 80 and over; Ampicillin/adverse effects; Anti-Bacterial Agents/adverse effects; Ceftriaxone/adverse effects; Cohort Studies; Drug Resistance, Bacterial; Drug Therapy, Combination/methods; Endocarditis/epidemiology; Endocarditis/microbiology; Enterococcus faecalis/drug effects; Female; Gentamicins/adverse effects; Gram-Positive Bacterial Infections/epidemiology; Gram-Positive Bacterial Infections/microbiology; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency/chemically induced; Renal Insufficiency/epidemiology; Spain/epidemiology; Survival Analysis; Treatment Outcome; Withholding Treatment

Key words

Ampicillin plus ceftriaxone; Enterococcus faecalis; antimicrobial treatment; high-level aminoglycoside resistance; infective endocarditis; outcomes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ceftriaxone / Gentamicins / Gram-Positive Bacterial Infections / Enterococcus faecalis / Endocarditis / Ampicillin / Anti-Bacterial Agents Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Clin Microbiol Infect Journal subject: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Year: 2014 Type: Article Affiliation country: Spain

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