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Novel inhibitors of human histone deacetylases: design, synthesis and bioactivity of 3-alkenoylcoumarines.
Seidel, Carole; Schnekenburger, Michael; Zwergel, Clemens; Gaascht, François; Mai, Antonello; Dicato, Mario; Kirsch, Gilbert; Valente, Sergio; Diederich, Marc.
Affiliation
  • Seidel C; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, L-2540 Luxembourg, Luxembourg.
  • Schnekenburger M; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, L-2540 Luxembourg, Luxembourg.
  • Zwergel C; UMR CNRS 7565 SRSMC, Université de Lorraine, 57070 Metz, France.
  • Gaascht F; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, L-2540 Luxembourg, Luxembourg.
  • Mai A; Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, P.le Aldo Moro 5, 00185 Roma, Italy.
  • Dicato M; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, L-2540 Luxembourg, Luxembourg.
  • Kirsch G; UMR CNRS 7565 SRSMC, Université de Lorraine, 57070 Metz, France.
  • Valente S; UMR CNRS 7565 SRSMC, Université de Lorraine, 57070 Metz, France; Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, P.le Aldo Moro 5, 00185 Roma, Italy. Electronic address: sergio.valente@uniroma1.it.
  • Diederich M; Department of Pharmacy, College of Pharmacy, Seoul National University, Building 20 Room 303, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Republic of Korea. Electronic address: marcdiederich@snu.ac.kr.
Bioorg Med Chem Lett ; 24(16): 3797-801, 2014 Aug 15.
Article in En | MEDLINE | ID: mdl-25042254
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Coumarins / Histone Deacetylase Inhibitors / Histone Deacetylases / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: Luxembourg
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Coumarins / Histone Deacetylase Inhibitors / Histone Deacetylases / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: Luxembourg