BDNF-ERK-CREB signalling mediates the role of miR-132 in the regulation of the effects of oleanolic acid in male mice.

Yi, Li-Tao; Li, Jing; Liu, Bin-Bin; Luo, Liu; Liu, Qing; Geng, Di

Yi, Li-Tao; Li, Jing; Liu, Bin-Bin; Luo, Liu; Liu, Qing; Geng, Di.

Affiliation

Yi LT; The Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Li J; The Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Liu BB; The Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Luo L; The Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Liu Q; The Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Geng D; The Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, China.

J Psychiatry Neurosci ; 39(5): 348-59, 2014 Sep.

Article in En | MEDLINE | ID: mdl-25079084

Subject(s)

Antidepressive Agents/pharmacology; Brain-Derived Neurotrophic Factor/metabolism; Cyclic AMP Response Element-Binding Protein/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; MicroRNAs/metabolism; Oleanolic Acid/pharmacology; Animals; Chronic Disease; Depressive Disorder/drug therapy; Depressive Disorder/physiopathology; Disease Models, Animal; Disks Large Homolog 4 Protein; Guanylate Kinases/metabolism; Hippocampus/drug effects; Hippocampus/physiopathology; Male; Membrane Proteins/metabolism; Mice, Inbred ICR; Neurogenesis/drug effects; Neurogenesis/physiology; Neurons/drug effects; Neurons/physiology; Random Allocation; Signal Transduction/drug effects; Stress, Psychological; Uncertainty; Up-Regulation/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oleanolic Acid / Cyclic AMP Response Element-Binding Protein / Brain-Derived Neurotrophic Factor / MicroRNAs / Extracellular Signal-Regulated MAP Kinases / Antidepressive Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Psychiatry Neurosci Journal subject: NEUROLOGIA / PSIQUIATRIA Year: 2014 Type: Article Affiliation country: China

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