Regional Multiple Pathology Scores Are Associated with Cognitive Decline in Lewy Body Dementias.

Howlett, David R; Whitfield, David; Johnson, Mary; Attems, Johannes; O'Brien, John T; Aarsland, Dag; Lai, Mitchell K P; Lee, Jasinda H; Chen, Christopher; Ballard, Clive; Hortobágyi, Tibor; Francis, Paul T

Howlett, David R; Whitfield, David; Johnson, Mary; Attems, Johannes; O'Brien, John T; Aarsland, Dag; Lai, Mitchell K P; Lee, Jasinda H; Chen, Christopher; Ballard, Clive; Hortobágyi, Tibor; Francis, Paul T.

Affiliation

Howlett DR; Wolfson Centre for Age-Related Diseases, King's College London, London, UK.
Whitfield D; Wolfson Centre for Age-Related Diseases, King's College London, London, UK.
Johnson M; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.
Attems J; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.
O'Brien JT; Department of Psychiatry, University of Cambridge, Cambridge, UK.
Aarsland D; Department of Neurobiology, Ward Sciences and Society, Karolinska Institute, Stockholm, Sweden.
Lai MK; Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway.
Lee JH; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Chen C; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ballard C; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Hortobágyi T; Wolfson Centre for Age-Related Diseases, King's College London, London, UK.
Francis PT; Wolfson Centre for Age-Related Diseases, King's College London, London, UK.

Brain Pathol ; 25(4): 401-8, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25103200

Subject(s)

Brain/pathology; Cognition Disorders/etiology; Cognition Disorders/pathology; Lewy Body Disease/complications; Aged; Aged, 80 and over; Amyloid beta-Peptides/metabolism; Brain/metabolism; Female; Humans; Lewy Body Disease/pathology; Male; Neurofibrillary Tangles/metabolism; Neurofibrillary Tangles/pathology; Phosphorylation; Plaque, Amyloid/metabolism; Plaque, Amyloid/pathology; alpha-Synuclein/metabolism; tau Proteins/metabolism

Key words

Alzheimer's disease; Lewy body dementia; Parkinson's disease dementia; cognitive decline; dementia with Lewy bodies

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Cognition Disorders / Lewy Body Disease Type of study: Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male Language: En Journal: Brain Pathol Journal subject: CEREBRO / PATOLOGIA Year: 2015 Type: Article Affiliation country: United kingdom

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