Efavirenz modulation of sleep spindles and sleep spectral profile.

Simen, Arthur A; Ma, Junshui; Svetnik, Vladimir; Mayleben, David; Maynard, James; Roth, Adam; Mixson, Lori; Mogg, Robin; Shera, David; George, Laura; Mast, T Chris; Beals, Chan; Stoch, Aubrey; Struyk, Arie; Shire, Norah; Fraser, Iain

Simen, Arthur A; Ma, Junshui; Svetnik, Vladimir; Mayleben, David; Maynard, James; Roth, Adam; Mixson, Lori; Mogg, Robin; Shera, David; George, Laura; Mast, T Chris; Beals, Chan; Stoch, Aubrey; Struyk, Arie; Shire, Norah; Fraser, Iain.

Affiliation

Simen AA; Merck Research Laboratories, Merck Sharp and Dohme, North Wales, PA, USA.

J Sleep Res ; 24(1): 66-73, 2015 Feb.

Article in En | MEDLINE | ID: mdl-25113527

Subject(s)

Benzoxazines/pharmacology; Sleep/drug effects; Sleep/physiology; Adult; Alkynes; Anti-HIV Agents/adverse effects; Anti-HIV Agents/pharmacology; Attention/drug effects; Attention/physiology; Benzoxazines/adverse effects; Cognition/drug effects; Cognition/physiology; Cyclopropanes; Drug Partial Agonism; Humans; Male; Middle Aged; Placebos; Receptor, Serotonin, 5-HT2A/metabolism; Reverse Transcriptase Inhibitors/adverse effects; Reverse Transcriptase Inhibitors/pharmacology; Serotonin 5-HT2 Receptor Antagonists/pharmacology; Wakefulness/drug effects; Wakefulness/physiology; Young Adult

Key words

central nervous system adverse events; daytime sleepiness; symptom questionnaire

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sleep / Benzoxazines Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Sleep Res Journal subject: PSICOFISIOLOGIA Year: 2015 Type: Article Affiliation country: United States

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