Pharmacogenetics of childhood acute lymphoblastic leukemia.

Lopez-Lopez, Elixabet; Gutierrez-Camino, Angela; Bilbao-Aldaiturriaga, Nerea; Pombar-Gomez, Maria; Martin-Guerrero, Idoia; Garcia-Orad, Africa

Lopez-Lopez, Elixabet; Gutierrez-Camino, Angela; Bilbao-Aldaiturriaga, Nerea; Pombar-Gomez, Maria; Martin-Guerrero, Idoia; Garcia-Orad, Africa.

Affiliation

Lopez-Lopez E; Department of Genetics, Physical Anthropology & Animal Physiology, Faculty of Medicine & Odontology, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, 48940 Leioa, Spain.

Pharmacogenomics ; 15(10): 1383-98, 2014 Jul.

Article in En | MEDLINE | ID: mdl-25155938

Subject(s)

Methotrexate/adverse effects; Pharmacogenetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Child; Child, Preschool; Epigenesis, Genetic; Humans; Methotrexate/therapeutic use; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology; Treatment Outcome

Key words

acute lymphoblastic leukemia; childhood; outcome; pharmacogenetics; toxicity; treatment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmacogenetics / Methotrexate / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Guideline Limits: Child / Child, preschool / Humans Language: En Journal: Pharmacogenomics Journal subject: FARMACOLOGIA / GENETICA MEDICA Year: 2014 Type: Article Affiliation country: Spain

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