Cytotoxic activity and degradation patterns of structural proteins by corneal isolates of Acanthamoeba spp.

Sant'ana, Viviane Peracini; Carrijo-Carvalho, Linda Christian; Foronda, Annette Silva; Chudzinski-Tavassi, Ana Marisa; de Freitas, Denise; de Carvalho, Fábio Ramos Souza

Sant'ana, Viviane Peracini; Carrijo-Carvalho, Linda Christian; Foronda, Annette Silva; Chudzinski-Tavassi, Ana Marisa; de Freitas, Denise; de Carvalho, Fábio Ramos Souza.

Affiliation

Sant'ana VP; Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of Sao Paulo, São Paulo, Brazil.

Graefes Arch Clin Exp Ophthalmol ; 253(1): 65-75, 2015 Jan.

Article in En | MEDLINE | ID: mdl-25161076

Subject(s)

Acanthamoeba Keratitis/parasitology; Acanthamoeba castellanii/enzymology; Fibronectins/metabolism; Laminin/metabolism; Protozoan Proteins/toxicity; Serine Proteases/toxicity; Tubulin/metabolism; Acanthamoeba castellanii/isolation & purification; Acanthamoeba castellanii/pathogenicity; Apoptosis/drug effects; Cell Membrane Permeability/drug effects; Cells, Cultured; Cornea/parasitology; Electrophoresis, Polyacrylamide Gel; Human Umbilical Vein Endothelial Cells/drug effects; Human Umbilical Vein Endothelial Cells/metabolism; Human Umbilical Vein Endothelial Cells/pathology; Humans; Proteolysis; Virulence Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tubulin / Acanthamoeba Keratitis / Protozoan Proteins / Fibronectins / Laminin / Acanthamoeba castellanii / Serine Proteases Type of study: Qualitative_research Limits: Humans Language: En Journal: Graefes Arch Clin Exp Ophthalmol Year: 2015 Type: Article Affiliation country: Brazil

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