Abnormalities in the zinc-metalloprotease-BDNF axis may contribute to megalencephaly and cortical hyperconnectivity in young autism spectrum disorder patients.

Koh, Jae-Young; Lim, Joon Seo; Byun, Hyae-Ran; Yoo, Min-Heui

Koh, Jae-Young; Lim, Joon Seo; Byun, Hyae-Ran; Yoo, Min-Heui.

Mol Brain ; 7: 64, 2014 Sep 03.

Article in En | MEDLINE | ID: mdl-25182223

Subject(s)

Brain-Derived Neurotrophic Factor/metabolism; Cerebral Cortex/physiopathology; Child Development Disorders, Pervasive/enzymology; Child Development Disorders, Pervasive/physiopathology; Megalencephaly/physiopathology; Metalloproteases/metabolism; Nerve Net/physiopathology; Zinc/metabolism; Cerebral Cortex/pathology; Child Development Disorders, Pervasive/pathology; Humans; Nerve Net/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zinc / Cerebral Cortex / Child Development Disorders, Pervasive / Brain-Derived Neurotrophic Factor / Metalloproteases / Megalencephaly / Nerve Net Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Brain Journal subject: BIOLOGIA MOLECULAR / CEREBRO Year: 2014 Type: Article

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