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Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging.
Sapir, Amir; Tsur, Assaf; Koorman, Thijs; Ching, Kaitlin; Mishra, Prashant; Bardenheier, Annabelle; Podolsky, Lisa; Bening-Abu-Shach, Ulrike; Boxem, Mike; Chou, Tsui-Fen; Broday, Limor; Sternberg, Paul W.
Affiliation
  • Sapir A; Division of Biology and Biological Engineering and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125;
  • Tsur A; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel;
  • Koorman T; Developmental Biology, Utrecht University, 3584 CH, Utrecht, The Netherlands; and.
  • Ching K; Division of Biology and Biological Engineering and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125;
  • Mishra P; Division of Biology and Biological Engineering and.
  • Bardenheier A; Division of Biology and Biological Engineering and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125;
  • Podolsky L; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel;
  • Bening-Abu-Shach U; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel;
  • Boxem M; Developmental Biology, Utrecht University, 3584 CH, Utrecht, The Netherlands; and.
  • Chou TF; Division of Medical Genetics, Department of Pediatrics, and Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA 90502.
  • Broday L; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; pws@caltech.edu broday@post.tau.ac.il.
  • Sternberg PW; Division of Biology and Biological Engineering and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125; pws@caltech.edu broday@post.tau.ac.il.
Proc Natl Acad Sci U S A ; 111(37): E3880-9, 2014 Sep 16.
Article in En | MEDLINE | ID: mdl-25187565
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Caenorhabditis elegans / Caenorhabditis elegans Proteins / Metabolic Networks and Pathways / Sumoylation / Hydroxymethylglutaryl-CoA Synthase / Mevalonic Acid Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Caenorhabditis elegans / Caenorhabditis elegans Proteins / Metabolic Networks and Pathways / Sumoylation / Hydroxymethylglutaryl-CoA Synthase / Mevalonic Acid Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Type: Article