Effects of ß-sitosterol derived from Artemisia capillaris on the activated human hepatic stellate cells and dimethylnitrosamine-induced mouse liver fibrosis.

Kim, Ki-Suk; Yang, Hea Jung; Lee, Jae-Youl; Na, Yun-Cheol; Kwon, Soo-Young; Kim, Young-Chul; Lee, Jang-Hoon; Jang, Hyeung-Jin

Kim, Ki-Suk; Yang, Hea Jung; Lee, Jae-Youl; Na, Yun-Cheol; Kwon, Soo-Young; Kim, Young-Chul; Lee, Jang-Hoon; Jang, Hyeung-Jin.

Affiliation

Lee JH; College of Korean Medicine, Institute of Korean Medicine, Kyung Hee University, 1 Heogi-dong, Dondaemun-gu, Seoul 130-701, Republic of Korea. komclive@khmc.or.kr.

BMC Complement Altern Med ; 14: 363, 2014 Sep 27.

Article in En | MEDLINE | ID: mdl-25262005

Subject(s)

Artemisia/chemistry; Hepatic Stellate Cells/drug effects; Liver Cirrhosis/metabolism; Plant Extracts/pharmacology; Sitosterols/pharmacology; Actins/analysis; Actins/genetics; Actins/metabolism; Animals; Cell Line; Cell Survival/drug effects; Collagen Type I/analysis; Collagen Type I/genetics; Collagen Type I/metabolism; Dimethylnitrosamine/adverse effects; Gene Expression/drug effects; Humans; Liver Cirrhosis/chemically induced; Male; Mice; Mice, Inbred C57BL; Plant Extracts/chemistry; Sitosterols/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sitosterols / Plant Extracts / Artemisia / Hepatic Stellate Cells / Liver Cirrhosis Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: BMC Complement Altern Med Journal subject: TERAPIAS COMPLEMENTARES Year: 2014 Type: Article

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