Prosurvival NMDA 2A receptor signaling mediates postconditioning neuroprotection in the hippocampus.

Zhang, Xi; Zhang, Quanguang; Tu, Jingyi; Zhu, Ying; Yang, Fang; Liu, Bin; Brann, Darrell; Wang, Ruimin

Zhang, Xi; Zhang, Quanguang; Tu, Jingyi; Zhu, Ying; Yang, Fang; Liu, Bin; Brann, Darrell; Wang, Ruimin.

Affiliation

Zhang X; Neurobiology Institute of Medical Research Center, Hebei United University, Tangshan, Hebei, 063000, China.

Hippocampus ; 25(3): 286-96, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25271147

Subject(s)

Brain Ischemia/metabolism; Brain Ischemia/pathology; Hippocampus/metabolism; Receptors, N-Methyl-D-Aspartate/metabolism; Signal Transduction/physiology; Analysis of Variance; Animals; Brain Ischemia/complications; Brain Ischemia/therapy; CREB-Binding Protein/metabolism; Calcium/metabolism; Dizocilpine Maleate/therapeutic use; Hippocampus/drug effects; Hippocampus/pathology; Immunoprecipitation; Male; Maze Learning/drug effects; Neuroprotective Agents/therapeutic use; Phenols/therapeutic use; Piperidines/therapeutic use; Quinoxalines/therapeutic use; Rats; Rats, Sprague-Dawley; Signal Transduction/drug effects; Time Factors

Key words

CREB; NMDA receptors; calcium; cerebral ischemic postconditioning; cognition

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Brain Ischemia / Receptors, N-Methyl-D-Aspartate / Hippocampus Limits: Animals Language: En Journal: Hippocampus Journal subject: CEREBRO Year: 2015 Type: Article Affiliation country: China

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