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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells.
Micci, Luca; Alvarez, Xavier; Iriele, Robin I; Ortiz, Alexandra M; Ryan, Emily S; McGary, Colleen S; Deleage, Claire; McAtee, Brigitte B; He, Tianyu; Apetrei, Cristian; Easley, Kirk; Pahwa, Savita; Collman, Ronald G; Derdeyn, Cynthia A; Davenport, Miles P; Estes, Jacob D; Silvestri, Guido; Lackner, Andrew A; Paiardini, Mirko.
Affiliation
  • Micci L; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Alvarez X; Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America.
  • Iriele RI; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Ortiz AM; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Ryan ES; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • McGary CS; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Deleage C; AIDS Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland, Maryland, United States of America.
  • McAtee BB; Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America.
  • He T; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Apetrei C; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Easley K; Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Atlanta, Georgia, United States of America.
  • Pahwa S; University of Miami Miller School of Medicine, Miami, Florida, United States of America.
  • Collman RG; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
  • Derdeyn CA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Davenport MP; Centre for Vascular Research, University of New South Wales, Kensington, New South Wales, Australia.
  • Estes JD; AIDS Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland, Maryland, United States of America.
  • Silvestri G; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Lackner AA; Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America.
  • Paiardini M; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
PLoS Pathog ; 10(10): e1004467, 2014 Oct.
Article in En | MEDLINE | ID: mdl-25356757
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Simian Acquired Immunodeficiency Syndrome / Simian Immunodeficiency Virus Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS Pathog Year: 2014 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Simian Acquired Immunodeficiency Syndrome / Simian Immunodeficiency Virus Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS Pathog Year: 2014 Type: Article Affiliation country: United States