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Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin.
Johnson-Kerner, Bethany L; Ahmad, Faizzan S; Diaz, Alejandro Garcia; Greene, John Palmer; Gray, Steven J; Samulski, Richard Jude; Chung, Wendy K; Van Coster, Rudy; Maertens, Paul; Noggle, Scott A; Henderson, Christopher E; Wichterle, Hynek.
Affiliation
  • Johnson-Kerner BL; Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, NY 10032, USA, Center for Motor Neuron Biology and Disease, Departments of Pathology and Cell Biology, Neurology, and Neuroscience, Columbia Stem Cell Initiative.
  • Ahmad FS; New York Stem Cell Foundation, New York, NY 10032, USA.
  • Diaz AG; Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, NY 10032, USA.
  • Greene JP; Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, NY 10032, USA.
  • Gray SJ; Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Samulski RJ; Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Chung WK; Department of Pediatrics and Medicine, Columbia University Medical Center, New York, NY 10032, USA.
  • Van Coster R; Department of Pediatrics, Division of Pediatric Neurology and Metabolism, Ghent University Hospital, Ghent, Belgium.
  • Maertens P; Departments of Pediatric Neurology, University of South Alabama, Mobile, AL, USA.
  • Noggle SA; New York Stem Cell Foundation, New York, NY 10032, USA.
  • Henderson CE; Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, NY 10032, USA, Center for Motor Neuron Biology and Disease, Departments of Pathology and Cell Biology, Neurology, and Neuroscience, Columbia Stem Cell Initiative, Department of Rehabilitation and Regenerative Medicine.
  • Wichterle H; Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, NY 10032, USA, Center for Motor Neuron Biology and Disease, Departments of Pathology and Cell Biology, Neurology, and Neuroscience, Columbia Stem Cell Initiative, hw350@columbia.edu.
Hum Mol Genet ; 24(5): 1420-31, 2015 Mar 01.
Article in En | MEDLINE | ID: mdl-25398950
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytoskeletal Proteins / Induced Pluripotent Stem Cells / Giant Axonal Neuropathy / Intermediate Filament Proteins / Motor Neurons Type of study: Prognostic_studies Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2015 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytoskeletal Proteins / Induced Pluripotent Stem Cells / Giant Axonal Neuropathy / Intermediate Filament Proteins / Motor Neurons Type of study: Prognostic_studies Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2015 Type: Article