Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy.

Meinke, Peter; Schneiderat, Peter; Srsen, Vlastimil; Korfali, Nadia; Lê Thành, Phú; Cowan, Graeme J M; Cavanagh, David R; Wehnert, Manfred; Schirmer, Eric C; Walter, Maggie C

Meinke, Peter; Schneiderat, Peter; Srsen, Vlastimil; Korfali, Nadia; Lê Thành, Phú; Cowan, Graeme J M; Cavanagh, David R; Wehnert, Manfred; Schirmer, Eric C; Walter, Maggie C.

Affiliation

Meinke P; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.
Schneiderat P; Friedrich-Baur-Institut, Department of Neurology, Ludwig-Maximilians-University of Munich, Munich, Germany.
Srsen V; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.
Korfali N; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.
Lê Thành P; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.
Cowan GJ; Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
Cavanagh DR; Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
Wehnert M; Institute of Human Genetics Greifswald, University Medicine, University of Greifswald, Germany (retired).
Schirmer EC; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK. Electronic address: e.schirmer@ed.ac.uk.
Walter MC; Friedrich-Baur-Institut, Department of Neurology, Ludwig-Maximilians-University of Munich, Munich, Germany. Electronic address: maggie.walter@lrz.uni-muenchen.de.

Neuromuscul Disord ; 25(2): 127-36, 2015 Feb.

Article in En | MEDLINE | ID: mdl-25454731

Subject(s)

Cell Differentiation/physiology; Cell Proliferation/physiology; Muscular Dystrophy, Emery-Dreifuss/pathology; Myoblasts/pathology; Adolescent; Adult; Age of Onset; Antigens, CD; Autoantigens/metabolism; Cardiomyopathies/etiology; Cell Cycle Proteins/metabolism; Cell Differentiation/genetics; Cell Proliferation/genetics; Cells, Cultured; Child; Family Health; Female; Flow Cytometry; Humans; Ki-67 Antigen/metabolism; Lamin Type A/metabolism; Magnetic Resonance Imaging; Male; Membrane Proteins/genetics; Membrane Proteins/metabolism; Muscular Dystrophy, Emery-Dreifuss/complications; Muscular Dystrophy, Emery-Dreifuss/genetics; Myoblasts/metabolism; Nuclear Proteins/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Transfection; Young Adult

Key words

EMD; Emerin; EmeryDreifuss muscular dystrophy; Myoblast differentiation; X-inactivation

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / Muscular Dystrophy, Emery-Dreifuss / Myoblasts / Cell Proliferation Type of study: Diagnostic_studies / Etiology_studies Limits: Adolescent / Adult / Child / Female / Humans / Male Language: En Journal: Neuromuscul Disord Journal subject: NEUROLOGIA Year: 2015 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google