Nanobody mediated inhibition of attachment of F18 Fimbriae expressing Escherichia coli.

Moonens, Kristof; De Kerpel, Maia; Coddens, Annelies; Cox, Eric; Pardon, Els; Remaut, Han; De Greve, Henri

Moonens, Kristof; De Kerpel, Maia; Coddens, Annelies; Cox, Eric; Pardon, Els; Remaut, Han; De Greve, Henri.

Affiliation

Moonens K; Structural & Molecular Microbiology, Structural Biology Research Center, VIB, Brussels, Belgium; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
De Kerpel M; Structural & Molecular Microbiology, Structural Biology Research Center, VIB, Brussels, Belgium; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
Coddens A; Department of Veterinary Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium.
Cox E; Department of Veterinary Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium.
Pardon E; Structural & Molecular Microbiology, Structural Biology Research Center, VIB, Brussels, Belgium; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
Remaut H; Structural & Molecular Microbiology, Structural Biology Research Center, VIB, Brussels, Belgium; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
De Greve H; Structural & Molecular Microbiology, Structural Biology Research Center, VIB, Brussels, Belgium; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

PLoS One ; 9(12): e114691, 2014.

Article in En | MEDLINE | ID: mdl-25502211

Subject(s)

Bacterial Adhesion/immunology; Escherichia coli/cytology; Escherichia coli/physiology; Fimbriae, Bacterial/metabolism; Single-Domain Antibodies/immunology; Adhesins, Bacterial/chemistry; Adhesins, Bacterial/immunology; Adhesins, Bacterial/metabolism; Animals; Binding, Competitive; Camelids, New World/immunology; Camelids, New World/microbiology; Carbohydrate Metabolism; Enterocytes/microbiology; Escherichia coli/immunology; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/immunology; Escherichia coli Proteins/metabolism; Fimbriae, Bacterial/immunology; Gene Expression; Models, Molecular; Protein Conformation; Single-Domain Antibodies/genetics; Swine/immunology; Swine/microbiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Adhesion / Fimbriae, Bacterial / Escherichia coli / Single-Domain Antibodies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Type: Article Affiliation country: Belgium

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