A multicenter, 12-month, open-label, single-arm safety study of oxycodone-hydrochloride/naltrexone-hydrochloride extended-release capsules (ALO-02) in patients with moderate-to-severe chronic noncancer pain.

Arora, Samir; Setnik, Beatrice; Michael, Drass; Hudson, John D; Clemmer, Ray; Meisner, Paul; Pixton, Glenn C; Goli, Veeraindar; Sommerville, Kenneth W

Arora, Samir; Setnik, Beatrice; Michael, Drass; Hudson, John D; Clemmer, Ray; Meisner, Paul; Pixton, Glenn C; Goli, Veeraindar; Sommerville, Kenneth W.

Affiliation

Arora S; Columbus Clinical Research, Columbus, Ohio.
Setnik B; Pfizer Inc., Durham, North Carolina.
Michael D; Allegheny Pain Management, Altoona, Pennsylvania.
Hudson JD; Future Search Trials of Neurology, Austin, Texas.
Clemmer R; Pfizer Inc., Groton, Connecticut.
Meisner P; Pfizer Inc., Durham, North Carolina.
Pixton GC; Pfizer Inc., Durham, North Carolina.
Goli V; Pfizer Inc., Durham, North Carolina; Duke University Medical Center, Durham, North Carolina.
Sommerville KW; Pfizer Inc., Durham, North Carolina; Duke University Medical Center, Durham, North Carolina.

J Opioid Manag ; 10(6): 423-36, 2014.

Article in En | MEDLINE | ID: mdl-25531960

Subject(s)

Analgesics, Opioid/administration & dosage; Chronic Pain/drug therapy; Naloxone/administration & dosage; Narcotic Antagonists/administration & dosage; Oxycodone/administration & dosage; Adult; Aged; Aged, 80 and over; Analgesics, Opioid/adverse effects; Analgesics, Opioid/chemistry; Analgesics, Opioid/pharmacokinetics; Capsules; Chemistry, Pharmaceutical; Chronic Pain/diagnosis; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Drug Monitoring; Female; Humans; Male; Middle Aged; Naloxone/adverse effects; Naloxone/chemistry; Naloxone/pharmacokinetics; Narcotic Antagonists/adverse effects; Narcotic Antagonists/chemistry; Narcotic Antagonists/pharmacokinetics; Oxycodone/adverse effects; Oxycodone/chemistry; Oxycodone/pharmacokinetics; Pain Measurement; Severity of Illness Index; Time Factors; Treatment Outcome; United States

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxycodone / Chronic Pain / Analgesics, Opioid / Naloxone / Narcotic Antagonists Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Aged80 Country/Region as subject: America do norte Language: En Journal: J Opioid Manag Journal subject: NEUROLOGIA / PSICOFISIOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2014 Type: Article

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