Ibrutinib-associated lymphocytosis corresponds to bone marrow involvement in mantle cell lymphoma.

Furtado, Michelle; Wang, Michael L; Munneke, Brian; McGreivy, Jesse; Beaupre, Darrin M; Rule, Simon

Furtado, Michelle; Wang, Michael L; Munneke, Brian; McGreivy, Jesse; Beaupre, Darrin M; Rule, Simon.

Affiliation

Furtado M; Plymouth University Schools of Medicine and Dentistry, Plymouth, Devon, UK.
Wang ML; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Munneke B; Pharmacyclics, Inc., Sunnyvale, CA, USA.
McGreivy J; Pharmacyclics, Inc., Sunnyvale, CA, USA.
Beaupre DM; Pharmacyclics, Inc., Sunnyvale, CA, USA.
Rule S; Plymouth University Schools of Medicine and Dentistry, Plymouth, Devon, UK. simon.rule@nhs.net.

Br J Haematol ; 170(1): 131-4, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25559624

Subject(s)

Bone Marrow/pathology; Lymphocytosis/etiology; Lymphoma, Mantle-Cell/pathology; Pyrazoles/adverse effects; Pyrimidines/adverse effects; Adenine/analogs & derivatives; Agammaglobulinaemia Tyrosine Kinase; Bone Marrow/enzymology; Bone Marrow/metabolism; Humans; Lymphocytosis/chemically induced; Lymphocytosis/pathology; Lymphoma, Mantle-Cell/drug therapy; Lymphoma, Mantle-Cell/enzymology; Piperidines; Protein-Tyrosine Kinases/antagonists & inhibitors; Pyrazoles/administration & dosage; Pyrimidines/administration & dosage

Key words

bone marrow; bruton tyrosine kinase inhibitor; ibrutinib; lymphocytosis; mantle cell lymphoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrimidines / Bone Marrow / Lymphoma, Mantle-Cell / Lymphocytosis Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Br J Haematol Year: 2015 Type: Article Affiliation country: United kingdom

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