Dehydrozingerone exerts beneficial metabolic effects in high-fat diet-induced obese mice via AMPK activation in skeletal muscle.

Kim, Su Jin; Kim, Hong Min; Lee, Eun Soo; Kim, Nami; Lee, Jung Ok; Lee, Hye Jeong; Park, Na Yeon; Jo, Joo Yeon; Ham, Bo Young; Han, Si Hyun; Park, Sun Hwa; Chung, Choon Hee; Kim, Hyeon Soo

Kim, Su Jin; Kim, Hong Min; Lee, Eun Soo; Kim, Nami; Lee, Jung Ok; Lee, Hye Jeong; Park, Na Yeon; Jo, Joo Yeon; Ham, Bo Young; Han, Si Hyun; Park, Sun Hwa; Chung, Choon Hee; Kim, Hyeon Soo.

Affiliation

Kim SJ; Department of Anatomy, Korea University College of Medicine, Seoul, South Korea.

J Cell Mol Med ; 19(3): 620-9, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25582026

Subject(s)

AMP-Activated Protein Kinases/metabolism; Glucose/metabolism; Muscle Fibers, Skeletal/metabolism; Styrenes/pharmacology; p38 Mitogen-Activated Protein Kinases/metabolism; AMP-Activated Protein Kinases/antagonists & inhibitors; AMP-Activated Protein Kinases/genetics; Animals; Biological Transport/drug effects; Biological Transport/genetics; Blood Glucose/metabolism; Cells, Cultured; Curcumin/analogs & derivatives; Deoxyglucose/metabolism; Diet, High-Fat; Enzyme Activation; Glucose Transporter Type 4/biosynthesis; Hyperglycemia/drug therapy; MAP Kinase Signaling System/drug effects; Male; Mice; Mice, Inbred C57BL; Obesity; Phosphorylation/drug effects; RNA Interference; RNA, Small Interfering; Rats; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors

Key words

AMPK; curcumin analogue; dehydrozingerone; glucose uptake; metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Styrenes / Muscle Fibers, Skeletal / P38 Mitogen-Activated Protein Kinases / AMP-Activated Protein Kinases / Glucose Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: South Korea

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