Effects of (R)-(-)-5-methyl-1-nicotinoyl-2-pyrazoline on glutamate transporter 1 and cysteine/glutamate exchanger as well as ethanol drinking behavior in male, alcohol-preferring rats.

Aal-Aaboda, Munaf; Alhaddad, Hasan; Osowik, Francis; Nauli, Surya M; Sari, Youssef

Aal-Aaboda, Munaf; Alhaddad, Hasan; Osowik, Francis; Nauli, Surya M; Sari, Youssef.

Affiliation

Aal-Aaboda M; Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, Ohio.

J Neurosci Res ; 93(6): 930-7, 2015 Jun.

Article in En | MEDLINE | ID: mdl-25601490

Subject(s)

Alcohol Drinking; Amino Acid Transport Systems, Acidic/metabolism; Down-Regulation/drug effects; Excitatory Amino Acid Transporter 2/metabolism; Nicotinic Acids/therapeutic use; Vitamin B Complex/therapeutic use; Alcohol Drinking/drug therapy; Alcohol Drinking/metabolism; Alcohol Drinking/pathology; Amygdala/drug effects; Amygdala/metabolism; Animals; Body Weight/drug effects; Central Nervous System Depressants/administration & dosage; Dose-Response Relationship, Drug; Drinking/drug effects; Drinking Behavior/drug effects; Ethanol/administration & dosage; Excitatory Amino Acid Transporter 2/genetics; Male; Rats; Tubulin/metabolism

Key words

GLT-1; MS-153; amygdala; glutamate; hippocampus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin B Complex / Alcohol Drinking / Down-Regulation / Amino Acid Transport Systems, Acidic / Excitatory Amino Acid Transporter 2 / Nicotinic Acids Limits: Animals Language: En Journal: J Neurosci Res Year: 2015 Type: Article

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