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Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.
Lee, Koon-Guan; Kim, Susana Soo-Yeon; Kui, Lin; Voon, Dominic Chih-Cheng; Mauduit, Marjorie; Bist, Pradeep; Bi, Xuezhi; Pereira, Natasha Ann; Liu, Chengcheng; Sukumaran, Bindu; Rénia, Laurent; Ito, Yoshiaki; Lam, Kong-Peng.
Affiliation
  • Lee KG; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore.
  • Kim SS; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore.
  • Kui L; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore.
  • Voon DC; Cancer Biology Program, Cancer Science Institute, National University of Singapore, Singapore 117599, Singapore.
  • Mauduit M; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore.
  • Bist P; Emerging Infectious Diseases Program, DUKE-NUS Graduate Medical School, Singapore 169857, Singapore.
  • Bi X; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore.
  • Pereira NA; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore.
  • Liu C; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore.
  • Sukumaran B; Emerging Infectious Diseases Program, DUKE-NUS Graduate Medical School, Singapore 169857, Singapore.
  • Rénia L; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore.
  • Ito Y; Cancer Biology Program, Cancer Science Institute, National University of Singapore, Singapore 117599, Singapore.
  • Lam KP; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore; Departments of Microbiology, Physiology, and Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117574, Singapore. Electronic address: lam_kong_peng@bt
Cell Rep ; 10(7): 1055-65, 2015 Feb 24.
Article in En | MEDLINE | ID: mdl-25704810
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / DNA / Interferon-beta / DEAD-box RNA Helicases / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2015 Type: Article Affiliation country: Singapore
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / DNA / Interferon-beta / DEAD-box RNA Helicases / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2015 Type: Article Affiliation country: Singapore