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Dissociable rate-dependent effects of oral methylphenidate on impulsivity and D2/3 receptor availability in the striatum.
Caprioli, Daniele; Jupp, Bianca; Hong, Young T; Sawiak, Stephen J; Ferrari, Valentina; Wharton, Laura; Williamson, David J; McNabb, Carolyn; Berry, David; Aigbirhio, Franklin I; Robbins, Trevor W; Fryer, Tim D; Dalley, Jeffrey W.
Affiliation
  • Caprioli D; Behavioral Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224.
  • Jupp B; Behavioural and Clinical Neuroscience Institute, and Department of Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom.
  • Hong YT; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, United Kingdom.
  • Sawiak SJ; Behavioural and Clinical Neuroscience Institute, and Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, United Kingdom.
  • Ferrari V; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, United Kingdom.
  • Wharton L; Behavioural and Clinical Neuroscience Institute, and Department of Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom.
  • Williamson DJ; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, United Kingdom.
  • McNabb C; School of Pharmacy, University of Auckland, Auckland 1142, New Zealand.
  • Berry D; Epilepsy Society, Chalfont St Peter SL9 0RJ, United Kingdom, and.
  • Aigbirhio FI; Behavioural and Clinical Neuroscience Institute, and Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, United Kingdom.
  • Robbins TW; Behavioural and Clinical Neuroscience Institute, and Department of Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom.
  • Fryer TD; Behavioural and Clinical Neuroscience Institute, and Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, United Kingdom.
  • Dalley JW; Behavioural and Clinical Neuroscience Institute, and Department of Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom, Department of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 2QQ, United Kingdom jwd20@cam.ac.uk.
J Neurosci ; 35(9): 3747-55, 2015 Mar 04.
Article in En | MEDLINE | ID: mdl-25740505
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Dopamine D2 / Dopamine Uptake Inhibitors / Corpus Striatum / Receptors, Dopamine D3 / Central Nervous System Stimulants / Impulsive Behavior / Methylphenidate Limits: Animals Language: En Journal: J Neurosci Year: 2015 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Dopamine D2 / Dopamine Uptake Inhibitors / Corpus Striatum / Receptors, Dopamine D3 / Central Nervous System Stimulants / Impulsive Behavior / Methylphenidate Limits: Animals Language: En Journal: J Neurosci Year: 2015 Type: Article