A Single-Center, Open-Label, 3-Way Crossover Trial to Determine the Pharmacokinetic and Pharmacodynamic Interaction Between Nebivolol and Valsartan in Healthy Volunteers at Steady State.

Chen, Chun Lin; Desai-Krieger, Daksha; Ortiz, Stephan; Kerolous, Majid; Wright, Harold M; Ghahramani, Parviz

Chen, Chun Lin; Desai-Krieger, Daksha; Ortiz, Stephan; Kerolous, Majid; Wright, Harold M; Ghahramani, Parviz.

Affiliation

Chen CL; Forest Research Institute, Inc, an affiliate of Actavis, Inc, Jersey City, NJ.

Am J Ther ; 22(5): e130-40, 2015.

Article in En | MEDLINE | ID: mdl-25853236

Subject(s)

Antihypertensive Agents/pharmacology; Nebivolol/pharmacology; Valsartan/pharmacology; Adolescent; Adult; Aldosterone/urine; Angiotensin II/blood; Antihypertensive Agents/administration & dosage; Antihypertensive Agents/pharmacokinetics; Area Under Curve; Cross-Over Studies; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Male; Middle Aged; Nebivolol/administration & dosage; Nebivolol/adverse effects; Nebivolol/pharmacokinetics; Pilot Projects; Pulse; Renin/blood; Valsartan/administration & dosage; Valsartan/adverse effects; Valsartan/pharmacokinetics; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nebivolol / Valsartan / Antihypertensive Agents Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Am J Ther Journal subject: TERAPEUTICA Year: 2015 Type: Article

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