Plasma concentrations of efavirenz, darunavir/ritonavir and raltegravir in HIV-HCV-coinfected patients without liver cirrhosis in comparison with HIV-monoinfected patients.

Calza, Leonardo; Danese, Ilaria; Colangeli, Vincenzo; Manfredi, Roberto; Magistrelli, Eleonora; Verucchi, Gabriella; Conti, Matteo; Motta, Roberto; Viale, Pierluigi

Calza, Leonardo; Danese, Ilaria; Colangeli, Vincenzo; Manfredi, Roberto; Magistrelli, Eleonora; Verucchi, Gabriella; Conti, Matteo; Motta, Roberto; Viale, Pierluigi.

Affiliation

Calza L; From the 1 Department of Medical and Surgical Sciences, Clinics of Infectious Diseases.

Infect Dis (Lond) ; 47(9): 625-36, 2015 Sep.

Article in En | MEDLINE | ID: mdl-25875396

Subject(s)

Anti-HIV Agents/blood; Benzoxazines/blood; Darunavir/blood; HIV Infections/drug therapy; Hepatitis C/complications; Raltegravir Potassium/blood; Ritonavir/blood; Adult; Alkynes; Analysis of Variance; Anti-HIV Agents/therapeutic use; Benzoxazines/pharmacokinetics; Benzoxazines/therapeutic use; Coinfection/drug therapy; Coinfection/epidemiology; Cyclopropanes; Darunavir/pharmacokinetics; Darunavir/therapeutic use; Female; HIV Infections/complications; HIV Infections/epidemiology; Hepatitis C/epidemiology; Humans; Liver Function Tests; Male; Middle Aged; Raltegravir Potassium/pharmacokinetics; Raltegravir Potassium/therapeutic use; Ritonavir/pharmacokinetics; Ritonavir/therapeutic use

Key words

Pharmacokinetics; integrase inhibitor; liver function; non-nucleoside reverse transcriptase inhibitor; protease inhibitor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Hepatitis C / Ritonavir / Anti-HIV Agents / Benzoxazines / Darunavir / Raltegravir Potassium Type of study: Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Infect Dis (Lond) Year: 2015 Type: Article

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