RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing.

Conde, João; Tian, Furong; Hernandez, Yulan; Bao, Chenchen; Baptista, Pedro V; Cui, Daxiang; Stoeger, Tobias; de la Fuente, Jesus M

Conde, João; Tian, Furong; Hernandez, Yulan; Bao, Chenchen; Baptista, Pedro V; Cui, Daxiang; Stoeger, Tobias; de la Fuente, Jesus M.

Affiliation

Conde J; Massachusetts Institute of Technology, Institute for Medical Engineering and Science, Harvard-MIT Division for Health Sciences and Technology, E25-449 Cambridge, Massachusetts, USA.

Nanoscale ; 7(19): 9083-91, 2015 May 21.

Article in En | MEDLINE | ID: mdl-25924183

Subject(s)

Glucose/chemistry; Metal Nanoparticles/chemistry; RNA Interference; RNA, Small Interfering/metabolism; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Gold/chemistry; Immunohistochemistry; Lung Neoplasms/diagnostic imaging; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Mice; Optical Imaging; Polyethylene Glycols/chemistry; Proto-Oncogene Proteins c-myc/antagonists & inhibitors; Proto-Oncogene Proteins c-myc/genetics; Proto-Oncogene Proteins c-myc/metabolism; RNA, Small Interfering/chemistry; Tomography, X-Ray Computed; fas Receptor/genetics; fas Receptor/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Small Interfering / RNA Interference / Metal Nanoparticles / Glucose Limits: Animals Language: En Journal: Nanoscale Year: 2015 Type: Article Affiliation country: United States

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