Insights into the development of molecular therapies for craniosynostosis.

Kosty, Jennifer; Vogel, Timothy W

Kosty, Jennifer; Vogel, Timothy W.

Affiliation

Kosty J; Department of Neurosurgery, University of Cincinnati; and.

Neurosurg Focus ; 38(5): E2, 2015 May.

Article in En | MEDLINE | ID: mdl-25929964

Subject(s)

Craniosynostoses/genetics; Craniosynostoses/therapy; Molecular Targeted Therapy/trends; Core Binding Factor Alpha 1 Subunit/genetics; Craniosynostoses/diagnosis; Humans; Molecular Targeted Therapy/methods; Mutation/genetics; Nuclear Proteins/genetics; Receptors, Fibroblast Growth Factor/genetics; Twist-Related Protein 1/genetics

Key words

BMP = bone morphogenetic protein; ERK1/2 = extracellular signal-related kinases 1 and 2; FGFR = fibroblast growth factor receptor; SNP = single nucleotide polymorphism; TGFß = transforming growth factor ß; TWIST; craniosynostosis; fibroblast growth factor receptor; genetics; molecular mechanisms; suture biology; therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Craniosynostoses / Molecular Targeted Therapy Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Neurosurg Focus Journal subject: NEUROCIRURGIA Year: 2015 Type: Article

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