DCC functions as an accelerator of thalamocortical axonal growth downstream of spontaneous thalamic activity.

Castillo-Paterna, Mar; Moreno-Juan, Verónica; Filipchuk, Anton; Rodríguez-Malmierca, Luis; Susín, Rafael; López-Bendito, Guillermina

Castillo-Paterna, Mar; Moreno-Juan, Verónica; Filipchuk, Anton; Rodríguez-Malmierca, Luis; Susín, Rafael; López-Bendito, Guillermina.

Affiliation

Castillo-Paterna M; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), San Joan d'Alacant, Spain.
Moreno-Juan V; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), San Joan d'Alacant, Spain.
Filipchuk A; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), San Joan d'Alacant, Spain.
Rodríguez-Malmierca L; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), San Joan d'Alacant, Spain.
Susín R; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), San Joan d'Alacant, Spain.
López-Bendito G; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), San Joan d'Alacant, Spain g.lbendito@umh.es.

EMBO Rep ; 16(7): 851-62, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25947198

Subject(s)

Axons/physiology; Receptors, Cell Surface/genetics; Receptors, Cell Surface/metabolism; Thalamus/physiology; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism; Animals; Axons/ultrastructure; Binding Sites; Calcium/metabolism; Cells, Cultured; DCC Receptor; Embryo, Mammalian; Gene Expression Regulation, Developmental; Growth Cones/physiology; Mice; NF-kappa B/metabolism; Nerve Growth Factors/metabolism; Netrin-1; Neurons/physiology; Promoter Regions, Genetic; Receptors, Cell Surface/chemistry; Signal Transduction; Thalamus/cytology; Thalamus/embryology; Tumor Suppressor Proteins/chemistry

Key words

Netrin1/Dcc signalling; axon growth; development; spontaneous activity; thalamus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Thalamus / Receptors, Cell Surface / Tumor Suppressor Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: EMBO Rep Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: Spain

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