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Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
Wang, Jieqi; Wegener, Jan Eike; Huang, Teng-Wei; Sripathy, Smitha; De Jesus-Cortes, Hector; Xu, Pin; Tran, Stephanie; Knobbe, Whitney; Leko, Vid; Britt, Jeremiah; Starwalt, Ruth; McDaniel, Latisha; Ward, Chris S; Parra, Diana; Newcomb, Benjamin; Lao, Uyen; Nourigat, Cynthia; Flowers, David A; Cullen, Sean; Jorstad, Nikolas L; Yang, Yue; Glaskova, Lena; Vingeau, Sébastien; Vigneau, Sebastian; Kozlitina, Julia; Yetman, Michael J; Jankowsky, Joanna L; Reichardt, Sybille D; Reichardt, Holger M; Gärtner, Jutta; Bartolomei, Marisa S; Fang, Min; Loeb, Keith; Keene, C Dirk; Bernstein, Irwin; Goodell, Margaret; Brat, Daniel J; Huppke, Peter; Neul, Jeffrey L; Bedalov, Antonio; Pieper, Andrew A.
Affiliation
  • Wang J; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Wegener JE; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
  • Huang TW; 1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Sripathy S; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • De Jesus-Cortes H; 1] Graduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA [2] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
  • Xu P; Graduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Tran S; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Knobbe W; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Leko V; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • Britt J; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
  • Starwalt R; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • McDaniel L; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
  • Ward CS; Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA.
  • Parra D; Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA.
  • Newcomb B; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • Lao U; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • Nourigat C; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • Flowers DA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • Cullen S; Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Jorstad NL; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
  • Yang Y; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
  • Glaskova L; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
  • Vigneau S; Department of Cell &Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Kozlitina J; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Yetman MJ; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Jankowsky JL; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Reichardt SD; Institute for Cellular and Molecular Immunology; University of Göttingen Medical School, Humboldtallee 34, 37073 Göttingen, Germany.
  • Reichardt HM; Institute for Cellular and Molecular Immunology; University of Göttingen Medical School, Humboldtallee 34, 37073 Göttingen, Germany.
  • Gärtner J; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
  • Bartolomei MS; Department of Cell &Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Fang M; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
  • Loeb K; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
  • Keene CD; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
  • Bernstein I; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • Goodell M; 1] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [2] Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA [3] Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA [4] Stem Cell and Regenerative Me
  • Brat DJ; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Huppke P; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
  • Neul JL; 1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [3] Department of Neuroscience, Baylor College of Medicine, Houston, Te
  • Bedalov A; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98105, USA.
  • Pieper AA; 1] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [2] Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [3] Veterans Affairs, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, US
Nature ; 521(7552): E1-4, 2015 May 21.
Article in En | MEDLINE | ID: mdl-25993969
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rett Syndrome / Microglia / Disease Progression / Methyl-CpG-Binding Protein 2 Limits: Animals Language: En Journal: Nature Year: 2015 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rett Syndrome / Microglia / Disease Progression / Methyl-CpG-Binding Protein 2 Limits: Animals Language: En Journal: Nature Year: 2015 Type: Article Affiliation country: United States