The prevalence of acute kidney injury in neonates with birth asphyxia is higher in the Democratic Republic of Congo than in Western countries.
Acta Paediatr
; 104(12): 1274-7, 2015 Dec.
Article
in En
| MEDLINE
| ID: mdl-26014304
ABSTRACT
AIM:
There is very little data on acute kidney injury in neonates in Africa. The aim of this study was to describe the frequency of acute kidney injury and the outcome in neonates admitted to hospital for asphyxia in the Democratic Republic of Congo.METHODS:
A descriptive study was conducted in the country's capital Kinshasa. Acute kidney injury was diagnosed within three days of life when the creatinine clearance was ≤16 mL/min/1.73 m².RESULTS:
Acute kidney injury occurred in 54.3% of the 35 neonates with severe perinatal asphyxia and 31.4% of the 35 neonates with moderate perinatal asphyxia, and this rate was higher than the prevalence reported in Western countries. Prerenal acute kidney injury occurred in 12 (40%) of the 30 neonates with acute kidney injury. The frequency of oliguria was significantly higher in neonates with severe perinatal asphyxia than moderate perinatal asphyxia (73.7% vs. 45.5%), and mortality was also higher in neonates with severe rather than moderate perinatal asphyxia (57.9% vs. 36.4%).CONCLUSION:
The prevalence of acute kidney injury was higher in asphyxiated patients in the Democratic Republic of Congo than in Western countries. It was also higher in neonates with severe rather than moderate perinatal asphyxia.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Asphyxia Neonatorum
/
Acute Kidney Injury
Type of study:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
/
Newborn
Country/Region as subject:
Africa
Language:
En
Journal:
Acta Paediatr
Year:
2015
Type:
Article