Network-based approaches for drug response prediction and targeted therapy development in cancer.

Dorel, Mathurin; Barillot, Emmanuel; Zinovyev, Andrei; Kuperstein, Inna

Dorel, Mathurin; Barillot, Emmanuel; Zinovyev, Andrei; Kuperstein, Inna.

Affiliation

Dorel M; Institut Curie, 26 rue d'Ulm, F-75248 Paris France; INSERM, U900, Paris, F-75248 France; Mines ParisTech, Fontainebleau, F-77300 France; Ecole Normale Supérieure, 46 rue d'Ulm, Paris, France.
Barillot E; Institut Curie, 26 rue d'Ulm, F-75248 Paris France; INSERM, U900, Paris, F-75248 France; Mines ParisTech, Fontainebleau, F-77300 France.
Zinovyev A; Institut Curie, 26 rue d'Ulm, F-75248 Paris France; INSERM, U900, Paris, F-75248 France; Mines ParisTech, Fontainebleau, F-77300 France.
Kuperstein I; Institut Curie, 26 rue d'Ulm, F-75248 Paris France; INSERM, U900, Paris, F-75248 France; Mines ParisTech, Fontainebleau, F-77300 France. Electronic address: Inna.Kuperstein@curie.fr.

Biochem Biophys Res Commun ; 464(2): 386-91, 2015 Aug 21.

Article in En | MEDLINE | ID: mdl-26086105

Subject(s)

Antineoplastic Agents/therapeutic use; Neoplasms/drug therapy; Drug Resistance, Neoplasm; Humans; Models, Theoretical; Neoplasms/metabolism; Signal Transduction

Key words

Cancer; Drug response; High-throughput data; Signaling network; Synthetic lethality; Targeted treatment

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2015 Type: Article Affiliation country: France

Fulltext

XML

PubMed Links

Search on Google