Immunoglobulin-like transcript 3 is expressed by myeloid-derived suppressor cells and correlates with survival in patients with non-small cell lung cancer.

de Goeje, Pauline L; Bezemer, Koen; Heuvers, Marlies E; Dingemans, Anne-Marie C; Groen, Harry Jm; Smit, Egbert F; Hoogsteden, Henk C; Hendriks, Rudi W; Aerts, Joachim Gjv; Hegmans, Joost Pjj

de Goeje, Pauline L; Bezemer, Koen; Heuvers, Marlies E; Dingemans, Anne-Marie C; Groen, Harry Jm; Smit, Egbert F; Hoogsteden, Henk C; Hendriks, Rudi W; Aerts, Joachim Gjv; Hegmans, Joost Pjj.

Affiliation

de Goeje PL; Erasmus MC Cancer Institute; Department of Pulmonary Medicine ; Rotterdam, The Netherlands.
Bezemer K; Erasmus MC Cancer Institute; Department of Pulmonary Medicine ; Rotterdam, The Netherlands.
Heuvers ME; Erasmus MC Cancer Institute; Department of Pulmonary Medicine ; Rotterdam, The Netherlands.
Dingemans AC; Maastricht University Medical Center; Department of Pulmonary Medicine ; Maastricht, The Netherlands.
Groen HJ; University of Groningen and University Medical Center Groningen; Department of Pulmonary Medicine ; Groningen, The Netherlands.
Smit EF; VU University Medical Center; Department of Pulmonary Medicine ; Amsterdam, The Netherlands ; Current address: Netherlands Cancer Institute; Department of Thoracic Oncology; Amsterdam, The Netherlands.
Hoogsteden HC; Erasmus MC Cancer Institute; Department of Pulmonary Medicine ; Rotterdam, The Netherlands.
Hendriks RW; Erasmus MC Cancer Institute; Department of Pulmonary Medicine ; Rotterdam, The Netherlands.
Aerts JG; Erasmus MC Cancer Institute; Department of Pulmonary Medicine ; Rotterdam, The Netherlands ; Amphia Hospital; Department of Pulmonary Medicine ; Breda, The Netherlands.
Hegmans JP; Erasmus MC Cancer Institute; Department of Pulmonary Medicine ; Rotterdam, The Netherlands.

Oncoimmunology ; 4(7): e1014242, 2015 Jul.

Article in En | MEDLINE | ID: mdl-26140237

Key words

APC, antigen-presenting cell; CD85k; DC, dendritic cell; ELISA, enzyme-linked immunosorbent assay; HC, healthy control; ILT3, immunoglobulin-like transcript 3; LILRB4; LIR-5; MDSC, myeloid-derived suppressor cell; MFI, mean fluorescence intensity; MO-MDSC, monocytic MDSC; NFκB, nuclear factor κB; NSCLC, non-small cell lung carcinoma; PBMC, peripheral blood mononuclear cell; PMN-MDSC, polymorphonuclear MDSC; Treg, regulatory T cell; Ts, T suppressor cell; immune suppression; immunoglobulin-like transcript 3; myeloid-derived suppressor cells; non-small cell lung cancer; overall survival; sILT3, soluble ILT3

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Oncoimmunology Year: 2015 Type: Article Affiliation country: Netherlands

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Oncoimmunology Year: 2015 Type: Article Affiliation country: Netherlands