Epstein-Barr virus-induced gene 3-deficiency leads to impaired antitumor T-cell responses and accelerated tumor growth.

Liu, Zhenzhen; Liu, Jin-Qing; Shi, Yun; Zhu, Xiaotong; Liu, Zhihao; Li, Ming-Song; Yu, Jianhua; Wu, Lai-Chu; He, Yukai; Zhang, Guoqiang; Bai, Xue-Feng

Liu, Zhenzhen; Liu, Jin-Qing; Shi, Yun; Zhu, Xiaotong; Liu, Zhihao; Li, Ming-Song; Yu, Jianhua; Wu, Lai-Chu; He, Yukai; Zhang, Guoqiang; Bai, Xue-Feng.

Affiliation

Liu Z; Department of Pathology and Comprehensive Cancer Center; Ohio State University ; Columbus, OH USA.
Liu JQ; Department of Pathology and Comprehensive Cancer Center; Ohio State University ; Columbus, OH USA.
Shi Y; Department of Pathology and Comprehensive Cancer Center; Ohio State University ; Columbus, OH USA ; Department of Gastroenterology; Guangdong Provincial Key Laboratory of Gastroenterology; Nanfang Hospital; Southern Medical University ; Guangzhou, China.
Zhu X; Department of Pathology and Comprehensive Cancer Center; Ohio State University ; Columbus, OH USA ; Department of Gastroenterology; Guangdong Provincial Key Laboratory of Gastroenterology; Nanfang Hospital; Southern Medical University ; Guangzhou, China.
Liu Z; Department of Pathology and Comprehensive Cancer Center; Ohio State University ; Columbus, OH USA ; Department of Hepatobiliary Surgery; Nanfang Hospital; Southern Medical University ; Guangzhou, China.
Li MS; Department of Gastroenterology; Guangdong Provincial Key Laboratory of Gastroenterology; Nanfang Hospital; Southern Medical University ; Guangzhou, China.
Yu J; Department of Pathology and Comprehensive Cancer Center; Ohio State University ; Columbus, OH USA.
Wu LC; Davis Medical Center; Department of Molecular and Cellular Biochemistry; Ohio State University ; Columbus, OH USA.
He Y; Cancer Immunology; Inflammation, and Tolerance Program; Georgia Regents University Cancer Center ; Augusta, GA USA.
Zhang G; Department of Thoracic Surgery; Xinqiao Hospital; Third Military Medical University ; Chongqing, China.
Bai XF; Department of Pathology and Comprehensive Cancer Center; Ohio State University ; Columbus, OH USA.

Oncoimmunology ; 4(7): e989137, 2015 Jul.

Article in En | MEDLINE | ID: mdl-26140252

Key words

APC, antigen-presenting cells; CTL, cytotoxic T lymphocyte; EBI3, Epstein-Barr virus-induced gene 3; Th, T helper; Treg, regulatory T cells.; Epstein-Barr virus-induced gene 3; IL-27; IL-35; Treg; tumor immunity

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