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Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer.
Sonnenblick, Amir; Brohée, Sylvain; Fumagalli, Debora; Vincent, Delphine; Venet, David; Ignatiadis, Michail; Salgado, Roberto; Van den Eynden, Gert; Rothé, Françoise; Desmedt, Christine; Neven, Patrick; Loibl, Sibylle; Denkert, Carsten; Joensuu, Heikki; Loi, Sherene; Sirtaine, Nicolas; Kellokumpu-Lehtinen, Pirkko-Liisa; Piccart, Martine; Sotiriou, Christos.
Affiliation
  • Sonnenblick A; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Brohée S; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Fumagalli D; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Vincent D; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Venet D; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Ignatiadis M; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Salgado R; Medical Oncology Unit, Institut Jules Bordet, Université Libre de Bruxelles, Bld de Waterloo, 1000, Brussels, Belgium.
  • Van den Eynden G; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Rothé F; Molecular Immunology Lab, Institut Jules Bordet, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Desmedt C; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Neven P; Breast Cancer Translational Research Laboratory J-C Heuson, Institut Jules Bordet, Bld de Waterloo, Université Libre de Bruxelles, 1000, Brussels, Belgium.
  • Loibl S; Multidisciplinary Breast Center, KULeuven, University Hospitals, Leuven, Belgium.
  • Denkert C; German Breast Group, Neu-Isenburg and Sana-Klinikum, Offenbach, Germany.
  • Joensuu H; Institute of Pathology, Charité Hospital Campus Mitte, and German Cancer Consortium (DKTK), Berlin, Germany.
  • Loi S; Department of Oncology, Helsinki University, Hospital and Helsinki University, Helsinki, Finland.
  • Sirtaine N; Division of Cancer Medicine and Research, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.
  • Kellokumpu-Lehtinen PL; Pathology Department, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Piccart M; Department of Oncology, University of Tampere and Tampere University Hospital, PO Box 607, FIN 33101, Tampere, Finland.
  • Sotiriou C; Medical Oncology Unit, Institut Jules Bordet, Université Libre de Bruxelles, Bld de Waterloo, 1000, Brussels, Belgium.
BMC Med ; 13: 177, 2015 Aug 03.
Article in En | MEDLINE | ID: mdl-26234940
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Breast Neoplasms / Receptor, ErbB-2 / Drug Resistance, Neoplasm / DNA-Binding Proteins / Antineoplastic Agents Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: BMC Med Journal subject: MEDICINA Year: 2015 Type: Article Affiliation country: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Breast Neoplasms / Receptor, ErbB-2 / Drug Resistance, Neoplasm / DNA-Binding Proteins / Antineoplastic Agents Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: BMC Med Journal subject: MEDICINA Year: 2015 Type: Article Affiliation country: Belgium