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Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer.
Garcia-Murillas, Isaac; Schiavon, Gaia; Weigelt, Britta; Ng, Charlotte; Hrebien, Sarah; Cutts, Rosalind J; Cheang, Maggie; Osin, Peter; Nerurkar, Ashutosh; Kozarewa, Iwanka; Garrido, Javier Armisen; Dowsett, Mitch; Reis-Filho, Jorge S; Smith, Ian E; Turner, Nicholas C.
Affiliation
  • Garcia-Murillas I; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.
  • Schiavon G; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.
  • Weigelt B; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Ng C; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Hrebien S; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.
  • Cutts RJ; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.
  • Cheang M; Institute of Cancer Research Clinical Trials and Statistics Unit, The Institute of Cancer Research, 15 Cotswold Road, Surrey SM2 5NG, UK.
  • Osin P; Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.
  • Nerurkar A; Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.
  • Kozarewa I; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.
  • Garrido JA; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.
  • Dowsett M; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.
  • Reis-Filho JS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Smith IE; Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.
  • Turner NC; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK. nicholas.turner@icr.ac.uk.
Sci Transl Med ; 7(302): 302ra133, 2015 Aug 26.
Article in En | MEDLINE | ID: mdl-26311728
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / DNA, Neoplasm / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / DNA, Neoplasm / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Type: Article Affiliation country: United kingdom