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Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity.
Caruso, Hillary G; Hurton, Lenka V; Najjar, Amer; Rushworth, David; Ang, Sonny; Olivares, Simon; Mi, Tiejuan; Switzer, Kirsten; Singh, Harjeet; Huls, Helen; Lee, Dean A; Heimberger, Amy B; Champlin, Richard E; Cooper, Laurence J N.
Affiliation
  • Caruso HG; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas.
  • Hurton LV; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas.
  • Najjar A; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Rushworth D; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas.
  • Ang S; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Olivares S; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Mi T; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Switzer K; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Singh H; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Huls H; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Lee DA; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas.
  • Heimberger AB; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Champlin RE; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Cooper LJ; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas. ljncooper@mdanderson.org ljncooper@ziopharm.com.
Cancer Res ; 75(17): 3505-18, 2015 Sep 01.
Article in En | MEDLINE | ID: mdl-26330164
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen / T-Lymphocytes / ErbB Receptors / Antigens, Neoplasm / Neoplasms Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2015 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen / T-Lymphocytes / ErbB Receptors / Antigens, Neoplasm / Neoplasms Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2015 Type: Article