Dissecting Complex and Multifactorial Nature of Alzheimer's Disease Pathogenesis: a Clinical, Genomic, and Systems Biology Perspective.

Talwar, Puneet; Sinha, Juhi; Grover, Sandeep; Rawat, Chitra; Kushwaha, Suman; Agarwal, Rachna; Taneja, Vibha; Kukreti, Ritushree

Talwar, Puneet; Sinha, Juhi; Grover, Sandeep; Rawat, Chitra; Kushwaha, Suman; Agarwal, Rachna; Taneja, Vibha; Kukreti, Ritushree.

Affiliation

Talwar P; Academy of Scientific and Innovative Research (AcSIR), CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB) Campus, New Delhi, India.
Sinha J; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, 110 007, India.
Grover S; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, 110 007, India.
Rawat C; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, 110 007, India.
Kushwaha S; Department of Paediatrics, Division of Pneumonology-Immunology, Charité University Medical Centre, Berlin, Germany.
Agarwal R; Academy of Scientific and Innovative Research (AcSIR), CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB) Campus, New Delhi, India.
Taneja V; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, 110 007, India.
Kukreti R; Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India.

Mol Neurobiol ; 53(7): 4833-64, 2016 09.

Article in En | MEDLINE | ID: mdl-26351077

Subject(s)

Alzheimer Disease/diagnosis; Alzheimer Disease/genetics; Genomics/methods; Systems Biology/trends; Alzheimer Disease/physiopathology; Amyloid beta-Peptides/genetics; Animals; Apolipoproteins E/genetics; Epigenomics/methods; Epigenomics/trends; Genetic Predisposition to Disease/genetics; Genome-Wide Association Study/methods; Genome-Wide Association Study/trends; Genomics/trends; Humans; Systems Biology/methods

Key words

Alzheimer's disease; Endophenotype; Epigenetics; Etiology; Genome-wide association; Genome-wide expression studies; Genome-wide linkage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genomics / Systems Biology / Alzheimer Disease Type of study: Etiology_studies / Prognostic_studies / Systematic_reviews Limits: Animals / Humans Language: En Journal: Mol Neurobiol Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2016 Type: Article Affiliation country: India

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