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Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Piegeler, T; Schläpfer, M; Dull, R O; Schwartz, D E; Borgeat, A; Minshall, R D; Beck-Schimmer, B.
Affiliation
  • Piegeler T; Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland Department of Anaesthesiology, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA.
  • Schläpfer M; Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland Institute of Physiology, Zurich Center for Integrative Human Physiology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Dull RO; Department of Anaesthesiology, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA Department of Bioengineering, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA.
  • Schwartz DE; Department of Anaesthesiology, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA.
  • Borgeat A; Department of Anaesthesiology, Balgrist Orthopaedic University Hospital Zurich, Forchstrasse 340, 8008 Zurich, Switzerland.
  • Minshall RD; Department of Anaesthesiology, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA Department of Pharmacology, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA Department of Bioengineering, University of Illinois at Chicago, 835 S. Wolcott Ave
  • Beck-Schimmer B; Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland Department of Anaesthesiology, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA Institute of Physiology, Zurich Center for Integrative Human Physiology, University of Zu
Br J Anaesth ; 115(5): 784-91, 2015 Nov.
Article in En | MEDLINE | ID: mdl-26475807
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Tumor Necrosis Factor-alpha / Amides / Anesthetics, Local / Lidocaine / Lung Neoplasms Limits: Humans Language: En Journal: Br J Anaesth Year: 2015 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Tumor Necrosis Factor-alpha / Amides / Anesthetics, Local / Lidocaine / Lung Neoplasms Limits: Humans Language: En Journal: Br J Anaesth Year: 2015 Type: Article Affiliation country: United States