Indications and immediate and long-term results of a novel pericardium covered stent graft: Consecutive 5 year single center experience.
Catheter Cardiovasc Interv
; 87(4): 712-9, 2016 Mar.
Article
in En
| MEDLINE
| ID: mdl-26541909
ABSTRACT
BACKGROUND:
The use of covered stent grafts during percutaneous coronary intervention (PCI) is a life saving solution to seal acute iatrogenic vessel rupture. However, the presence of an impenetrable mechanical barrier is also appealing during treatment of friable coronary plaques but the synthetic PTFE-membrane that might trigger excessive neointimal proliferation has limited its elective-use. Pericardium tissue may offer an appealing "natural" alternative. Aim of our study is to report the consecutive 5-year single center experience with the use of pericardium-covered stents (PCS) (ITGI-Medical, Israel) in a variety of emergency and elective applications.METHODS:
Nineteen consecutive patients undergoing implantation of PCS at the Royal Brompton in the last 5-years. Reasons for PCS implantation included treatment of degenerated vein grafts, large coronary aneurysms, and acute iatrogenic vessel rupture.RESULTS:
Angiographic success, defined as the ability of the device to be deployed in the indexed lesion with no contrast extravasation with residual angiographic stenosis <30% and a final thrombolysis in myocardial infarction (TIMI)-3 flow was achieved in all cases. Procedural success, defined as the achievement of angiographic success without any major adverse cardiovascular event (MACE) was achieved in 94.7% of patients. In-stent restenosis (ISR) was observed in 26.3% and all patients underwent successful target vessel revascularization with DES (mean time to restenosis 9.0 ± 4.0 months). At a mean follow-up of 32.5 ± 23.3 months no acute or late stent thrombosis was observed.CONCLUSION:
PCSs were effective in the treatment of friable embolization-prone coronary plaques, sealing of acute iatrogenic vessel rupture and exclusion of large aneurysms with no thrombosis but high target lesion revascularization.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pericardium
/
Saphenous Vein
/
Coronary Aneurysm
/
Coronary Artery Disease
/
Angioplasty, Balloon, Coronary
/
Stents
/
Coronary Vessels
/
Coated Materials, Biocompatible
/
Vascular System Injuries
/
Iatrogenic Disease
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Aged80
Country/Region as subject:
Europa
Language:
En
Journal:
Catheter Cardiovasc Interv
Journal subject:
CARDIOLOGIA
Year:
2016
Type:
Article
Affiliation country:
United kingdom