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Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.
Wertz, Ingrid E; Newton, Kim; Seshasayee, Dhaya; Kusam, Saritha; Lam, Cynthia; Zhang, Juan; Popovych, Nataliya; Helgason, Elizabeth; Schoeffler, Allyn; Jeet, Surinder; Ramamoorthi, Nandhini; Kategaya, Lorna; Newman, Robert J; Horikawa, Keisuke; Dugger, Debra; Sandoval, Wendy; Mukund, Susmith; Zindal, Anuradha; Martin, Flavius; Quan, Clifford; Tom, Jeffrey; Fairbrother, Wayne J; Townsend, Michael; Warming, Søren; DeVoss, Jason; Liu, Jinfeng; Dueber, Erin; Caplazi, Patrick; Lee, Wyne P; Goodnow, Christopher C; Balazs, Mercedesz; Yu, Kebing; Kolumam, Ganesh; Dixit, Vishva M.
Affiliation
  • Wertz IE; Discovery Oncology, Genentech, South San Francisco, California 94080, USA.
  • Newton K; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Seshasayee D; Physiological Chemistry, Genentech, South San Francisco, California 94080, USA.
  • Kusam S; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Lam C; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Zhang J; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Popovych N; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Helgason E; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Schoeffler A; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Jeet S; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Ramamoorthi N; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Kategaya L; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Newman RJ; Discovery Oncology, Genentech, South San Francisco, California 94080, USA.
  • Horikawa K; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Dugger D; Molecular Biology, Genentech, South San Francisco, California 94080, USA.
  • Sandoval W; Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory 2601, Australia.
  • Mukund S; Physiological Chemistry, Genentech, South San Francisco, California 94080, USA.
  • Zindal A; Protein Chemistry, Genentech, South San Francisco, California 94080, USA.
  • Martin F; Structural Biology, Genentech, South San Francisco, California 94080, USA.
  • Quan C; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Tom J; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Fairbrother WJ; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Townsend M; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Warming S; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • DeVoss J; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Liu J; Molecular Biology, Genentech, South San Francisco, California 94080, USA.
  • Dueber E; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Caplazi P; Bioinformatics, Genentech, South San Francisco, California 94080, USA.
  • Lee WP; Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, USA.
  • Goodnow CC; Pathology, Genentech, South San Francisco, California 94080, USA.
  • Balazs M; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Yu K; Immunogenomics Laboratory, Immunology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Sydney, Australia.
  • Kolumam G; Immunology, Genentech, South San Francisco, California 94080, USA.
  • Dixit VM; Protein Chemistry, Genentech, South San Francisco, California 94080, USA.
Nature ; 528(7582): 370-5, 2015 Dec 17.
Article in En | MEDLINE | ID: mdl-26649818
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cysteine Endopeptidases / Ubiquitin / Intracellular Signaling Peptides and Proteins / Inflammation Limits: Animals Language: En Journal: Nature Year: 2015 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cysteine Endopeptidases / Ubiquitin / Intracellular Signaling Peptides and Proteins / Inflammation Limits: Animals Language: En Journal: Nature Year: 2015 Type: Article Affiliation country: United States