Reappraisal of hMLH1 promoter methylation and protein expression status in the serrated neoplasia pathway.

Lee, Eun-Jung; Chun, Sung-Min; Kim, Mi-Jung; Jang, Se-Jin; Kim, Do Sun; Lee, Doo Han; Youk, Eui Gon

Lee, Eun-Jung; Chun, Sung-Min; Kim, Mi-Jung; Jang, Se-Jin; Kim, Do Sun; Lee, Doo Han; Youk, Eui Gon.

Affiliation

Lee EJ; Department of Surgery, Daehang Hospital, Seoul, Korea.
Chun SM; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kim MJ; Department of Pathology, Daehang Hospital, Seoul, Korea.
Jang SJ; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kim do S; Department of Surgery, Daehang Hospital, Seoul, Korea.
Lee DH; Department of Surgery, Daehang Hospital, Seoul, Korea.
Youk EG; Department of Surgery, Daehang Hospital, Seoul, Korea.

Histopathology ; 69(2): 198-210, 2016 Aug.

Article in En | MEDLINE | ID: mdl-26713412

Subject(s)

Adenoma/metabolism; Colonic Polyps/metabolism; Colorectal Neoplasms/metabolism; Hyperplasia/metabolism; MutL Protein Homolog 1/metabolism; Promoter Regions, Genetic/genetics; Adenoma/diagnosis; Adenoma/pathology; Adult; Aged; Aged, 80 and over; Colonic Polyps/diagnosis; Colonic Polyps/pathology; Colorectal Neoplasms/diagnosis; Colorectal Neoplasms/pathology; DNA Methylation; Female; Humans; Hyperplasia/diagnosis; Hyperplasia/pathology; Immunohistochemistry; Male; Middle Aged; MutL Protein Homolog 1/genetics

Key words

colon; dysplasia; hMLH1; hyperplastic polyp; sessile serrated adenoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Adenoma / Colonic Polyps / Promoter Regions, Genetic / MutL Protein Homolog 1 / Hyperplasia Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Histopathology Year: 2016 Type: Article

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