Nonhematopoietic Peroxisome Proliferator-Activated Receptor-&#945; Protects Against Cardiac Injury and Enhances Survival in Experimental Polymicrobial Sepsis.

Standage, Stephen W; Waworuntu, Rachel L; Delaney, Martha A; Maskal, Sara M; Bennion, Brock G; Duffield, Jeremy S; Parks, William C; Liles, W Conrad; McGuire, John K

Nonhematopoietic Peroxisome Proliferator-Activated Receptor-α Protects Against Cardiac Injury and Enhances Survival in Experimental Polymicrobial Sepsis.

Standage, Stephen W; Waworuntu, Rachel L; Delaney, Martha A; Maskal, Sara M; Bennion, Brock G; Duffield, Jeremy S; Parks, William C; Liles, W Conrad; McGuire, John K.

Affiliation

Standage SW; 1Center for Lung Biology, Department of Medicine, University of Washington School of Medicine, Seattle, WA. 2Department of Pediatrics (Critical Care Medicine), University of Washington School of Medicine, Seattle, WA. 3Department of Comparative Medicine, University of Washington School of Medicine, Seattle, WA. 4Department of Medicine, University of Washington School of Medicine, Seattle, WA.

Crit Care Med ; 44(8): e594-603, 2016 08.

Article in En | MEDLINE | ID: mdl-26757163

Subject(s)

PPAR alpha/biosynthesis; PPAR alpha/genetics; Sepsis/genetics; Sepsis/mortality; Animals; Behavior, Animal; Blood Glucose; Body Weight; Bone Marrow Transplantation; Disease Models, Animal; Down-Regulation; Gene Expression; Health Status; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium/pathology; Prospective Studies; Random Allocation; Sepsis/physiopathology; Troponin I/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sepsis / PPAR alpha Type of study: Observational_studies / Prognostic_studies Limits: Animals Language: En Journal: Crit Care Med Year: 2016 Type: Article

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