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Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture.
Geens, M; Seriola, A; Barbé, L; Santalo, J; Veiga, A; Dée, K; Van Haute, L; Sermon, K; Spits, C.
Affiliation
  • Geens M; Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Jette, Belgium mieke.geens@vub.ac.be.
  • Seriola A; Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Jette, Belgium Departament de Biologia Cellular, Fisiologia i Immunologia, Facultat de Biociències, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain Center for Regenerative Medicine in Barcelona, 0
  • Barbé L; Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Jette, Belgium.
  • Santalo J; Departament de Biologia Cellular, Fisiologia i Immunologia, Facultat de Biociències, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
  • Veiga A; Center for Regenerative Medicine in Barcelona, 08003 Barcelona, Spain.
  • Dée K; Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Jette, Belgium.
  • Van Haute L; Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Jette, Belgium MRC Mitochondrial Biology Unit, Hills Road, Cambridge, UK.
  • Sermon K; Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Jette, Belgium.
  • Spits C; Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Jette, Belgium.
Mol Hum Reprod ; 22(4): 285-98, 2016 Apr.
Article in En | MEDLINE | ID: mdl-26786180
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Pluripotent Stem Cells / Epigenesis, Genetic / X Chromosome Inactivation / RNA, Long Noncoding Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Mol Hum Reprod Journal subject: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Year: 2016 Type: Article Affiliation country: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Pluripotent Stem Cells / Epigenesis, Genetic / X Chromosome Inactivation / RNA, Long Noncoding Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Mol Hum Reprod Journal subject: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Year: 2016 Type: Article Affiliation country: Belgium