Let It Go and Open Up, an Ensemble of Ion Channel Active States.
Cell
; 164(4): 597-8, 2016 Feb 11.
Article
in En
| MEDLINE
| ID: mdl-26871624
Ligand binding usually moves the target protein from an ensemble of inactive states to a well-defined active conformation. Matthies et al. flip this scheme around, finding that, for the magnesium channel CorA, loss of ligand binding induces an ensemble of conformations that turn the channel on.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacterial Proteins
/
Thermotoga maritima
/
Cation Transport Proteins
/
Magnesium
Language:
En
Journal:
Cell
Year:
2016
Type:
Article