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Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors.
Huang, Fei; Goyal, Nadish; Sullivan, Katherine; Hanamshet, Kritika; Patel, Mikir; Mazina, Olga M; Wang, Charles X; An, W Frank; Spoonamore, James; Metkar, Shailesh; Emmitte, Kyle A; Cocklin, Simon; Skorski, Tomasz; Mazin, Alexander V.
Affiliation
  • Huang F; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.
  • Goyal N; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.
  • Sullivan K; Department of Microbiology and Immunology, and Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, PA 10140, USA.
  • Hanamshet K; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.
  • Patel M; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.
  • Mazina OM; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.
  • Wang CX; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.
  • An WF; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Spoonamore J; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Metkar S; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Emmitte KA; Vanderbilt Specialized Chemistry Center for Accelerated Probe Development, Vanderbilt Center for Neuroscience Drug Discovery, Department of Pharmacology and Chemistry, Vanderbilt University, Nashville, TN 37232, USA.
  • Cocklin S; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.
  • Skorski T; Department of Microbiology and Immunology, and Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, PA 10140, USA.
  • Mazin AV; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA Alexander.Mazin@DrexelMed.edu.
Nucleic Acids Res ; 44(9): 4189-99, 2016 05 19.
Article in En | MEDLINE | ID: mdl-26873923
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: BRCA1 Protein / BRCA2 Protein / Rad52 DNA Repair and Recombination Protein / Antineoplastic Agents Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2016 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: BRCA1 Protein / BRCA2 Protein / Rad52 DNA Repair and Recombination Protein / Antineoplastic Agents Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2016 Type: Article Affiliation country: United States