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Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis.
Valenzuela, Nicolas; Fan, Qiying; Fa'ak, Faisal; Soibam, Benjamin; Nagandla, Harika; Liu, Yu; Schwartz, Robert J; McConnell, Bradley K; Stewart, M David.
Affiliation
  • Valenzuela N; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
  • Fan Q; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
  • Fa'ak F; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
  • Soibam B; Department of Computer Science and Engineering Technology, University of Houston-Downtown, Houston, TX 77002, USA.
  • Nagandla H; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
  • Liu Y; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
  • Schwartz RJ; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA Stem Cell Engineering Department, Texas Heart Institute at St Luke's Episcopal Hospital, Houston, TX 77030, USA.
  • McConnell BK; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
  • Stewart MD; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA dstewart@uh.edu.
Dis Model Mech ; 9(3): 335-45, 2016 Mar.
Article in En | MEDLINE | ID: mdl-26935106
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcolemma / Transcription Factors / Cardiomegaly / Cell Cycle Proteins / Myocytes, Cardiac / Histone Chaperones Limits: Animals Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2016 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcolemma / Transcription Factors / Cardiomegaly / Cell Cycle Proteins / Myocytes, Cardiac / Histone Chaperones Limits: Animals Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2016 Type: Article Affiliation country: United States