Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-&#954;B signaling pathway in experimental traumatic brain injury.

Feng, Yan; Cui, Ying; Gao, Jun-Ling; Li, Ming-Hang; Li, Ran; Jiang, Xiao-Hua; Tian, Yan-Xia; Wang, Kai-Jie; Cui, Chang-Meng; Cui, Jian-Zhong

Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury.

Feng, Yan; Cui, Ying; Gao, Jun-Ling; Li, Ming-Hang; Li, Ran; Jiang, Xiao-Hua; Tian, Yan-Xia; Wang, Kai-Jie; Cui, Chang-Meng; Cui, Jian-Zhong.

Affiliation

Feng Y; Department of Surgery, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Cui Y; Department of Neurosurgery,Tangshan Workers' Hospital, Tangshan, Hebei 063000, P.R. China.
Gao JL; School of Basic Medical Science, Hebei United University, Tangshan, Hebei 063000, P.R. China.
Li MH; School of Basic Medical Science, Hebei United University, Tangshan, Hebei 063000, P.R. China.
Li R; School of Basic Medical Science, Hebei United University, Tangshan, Hebei 063000, P.R. China.
Jiang XH; School of Basic Medical Science, Hebei United University, Tangshan, Hebei 063000, P.R. China.
Tian YX; School of Basic Medical Science, Hebei United University, Tangshan, Hebei 063000, P.R. China.
Wang KJ; Department of Neurosurgery,Tangshan Workers' Hospital, Tangshan, Hebei 063000, P.R. China.
Cui CM; Department of Surgery, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Cui JZ; Department of Surgery, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.

Int J Mol Med ; 37(4): 921-30, 2016 Apr.

Article in En | MEDLINE | ID: mdl-26936125

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Brain Injuries, Traumatic/drug therapy; Brain/drug effects; NF-kappa B/antagonists & inhibitors; Neuroprotective Agents/therapeutic use; Stilbenes/therapeutic use; Toll-Like Receptor 4/antagonists & inhibitors; Animals; Autophagy/drug effects; Brain/immunology; Brain/pathology; Brain/physiopathology; Brain Injuries, Traumatic/immunology; Brain Injuries, Traumatic/pathology; Brain Injuries, Traumatic/physiopathology; Male; Memory/drug effects; Motor Activity/drug effects; NF-kappa B/analysis; NF-kappa B/immunology; Neurons/drug effects; Neurons/immunology; Neurons/pathology; Rats, Sprague-Dawley; Resveratrol; Toll-Like Receptor 4/analysis; Toll-Like Receptor 4/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stilbenes / Brain / Anti-Inflammatory Agents, Non-Steroidal / NF-kappa B / Neuroprotective Agents / Toll-Like Receptor 4 / Brain Injuries, Traumatic Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2016 Type: Article

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