The 3D Genome as Moderator of Chromosomal Communication.

Dekker, Job; Mirny, Leonid

Dekker, Job; Mirny, Leonid.

Affiliation

Dekker J; Howard Hughes Medical Institute, Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA, 01605-0103, USA. Electronic address: job.dekker@umassmed.edu.
Mirny L; Institute for Medical Engineering and Science and Department of Physics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, E25-526C, Cambridge, MA 02139, USA. Electronic address: leonid@mit.edu.

Cell ; 164(6): 1110-1121, 2016 Mar 10.

Article in En | MEDLINE | ID: mdl-26967279

Subject(s)

Chromosomes/metabolism; Genome; Adenosine Triphosphatases/metabolism; Animals; CCCTC-Binding Factor; DNA-Binding Proteins/metabolism; Female; Humans; Mitosis; Multiprotein Complexes/metabolism; Repressor Proteins; X Chromosome Inactivation

Key words

CTCF; Hi-C; biophysics; cohesin; condensin; domains; enhancer; gene expression; gene regulation; polymers; promoter; simulations

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes / Genome Limits: Animals / Female / Humans Language: En Journal: Cell Year: 2016 Type: Article

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