A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading.

Reho, John J; Kenchegowda, Doreswamy; Asico, Laureano D; Fisher, Steven A

Reho, John J; Kenchegowda, Doreswamy; Asico, Laureano D; Fisher, Steven A.

Affiliation

Reho JJ; Department of Medicine, Divisions of Cardiovascular Medicine and Nephrology, University of Maryland-Baltimore, Baltimore, Maryland.
Kenchegowda D; Department of Medicine, Divisions of Cardiovascular Medicine and Nephrology, University of Maryland-Baltimore, Baltimore, Maryland.
Asico LD; Department of Medicine, Divisions of Cardiovascular Medicine and Nephrology, University of Maryland-Baltimore, Baltimore, Maryland.
Fisher SA; Department of Medicine, Divisions of Cardiovascular Medicine and Nephrology, University of Maryland-Baltimore, Baltimore, Maryland sfisher1@medicine.umaryland.edu.

Am J Physiol Heart Circ Physiol ; 310(11): H1715-24, 2016 06 01.

Article in En | MEDLINE | ID: mdl-27084390

Subject(s)

Mesenteric Arteries/metabolism; Myosin-Light-Chain Phosphatase/metabolism; Vasodilation/drug effects; Alleles; Alternative Splicing; Animals; Mesenteric Arteries/drug effects; Mice; Mice, Knockout; Muscle, Smooth, Vascular/drug effects; Muscle, Smooth, Vascular/metabolism; Myosin-Light-Chain Phosphatase/genetics; Protein Isoforms/metabolism; Sodium Chloride/pharmacology

Key words

blood pressure; cGMP; mesenteric artery; nitric oxide; smooth muscle

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vasodilation / Myosin-Light-Chain Phosphatase / Mesenteric Arteries Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2016 Type: Article

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