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Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3.
Song, Xianzhou; Chen, Jianwei; Zhao, Mingkun; Zhang, Chengwei; Yu, Yang; Lonard, David M; Chow, Dar-Chone; Palzkill, Timothy; Xu, Jianming; O'Malley, Bert W; Wang, Jin.
Affiliation
  • Song X; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030;
  • Chen J; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030;
  • Zhao M; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030; Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX 77030;
  • Zhang C; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030;
  • Yu Y; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030;
  • Lonard DM; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030.
  • Chow DC; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030.
  • Palzkill T; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030.
  • Xu J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030;
  • O'Malley BW; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030 berto@bcm.edu wangj@bcm.edu.
  • Wang J; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030 berto@bcm.edu wangj@bcm.edu.
Proc Natl Acad Sci U S A ; 113(18): 4970-5, 2016 May 03.
Article in En | MEDLINE | ID: mdl-27084884
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Nuclear Receptor Coactivator 3 / Hydrazones Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Nuclear Receptor Coactivator 3 / Hydrazones Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Type: Article