Sciatic nerve regeneration in KLF7-transfected acellular nerve allografts.

Wang, Ying; Li, Wen-Yuan; Sun, Ping; Jin, Zai-Shun; Liu, Gui-Bo; Deng, Ling-Xiao; Guan, Li-Xin

Wang, Ying; Li, Wen-Yuan; Sun, Ping; Jin, Zai-Shun; Liu, Gui-Bo; Deng, Ling-Xiao; Guan, Li-Xin.

Affiliation

Wang Y; a Department of Anatomy, Mudanjiang College of Medicine , Mudanjiang College of Medicine , Mudanjiang , China.
Li WY; a Department of Anatomy, Mudanjiang College of Medicine , Mudanjiang College of Medicine , Mudanjiang , China.
Sun P; a Department of Anatomy, Mudanjiang College of Medicine , Mudanjiang College of Medicine , Mudanjiang , China.
Jin ZS; a Department of Anatomy, Mudanjiang College of Medicine , Mudanjiang College of Medicine , Mudanjiang , China.
Liu GB; a Department of Anatomy, Mudanjiang College of Medicine , Mudanjiang College of Medicine , Mudanjiang , China.
Deng LX; b Stark Neurosciences Research Institute , Indiana University School of Medicine , Indianapolis , USA.
Guan LX; c Department of Pharmacy , Mudanjiang College of Medicine , Tongxiang Road, Aimin District, Mudanjiang 157011 , Heilongjiang , China.

Neurol Res ; 38(3): 242-54, 2016 Mar.

Article in En | MEDLINE | ID: mdl-27093235

Subject(s)

Allografts/metabolism; Gene Expression Regulation/genetics; Kruppel-Like Transcription Factors/metabolism; Nerve Regeneration/physiology; Sciatic Neuropathy/surgery; Allografts/ultrastructure; Animals; Cholera Toxin/metabolism; Dependovirus/genetics; Disease Models, Animal; Female; Ganglia, Spinal/metabolism; Ganglia, Spinal/pathology; Glial Fibrillary Acidic Protein/metabolism; Intermediate Filaments/metabolism; Kruppel-Like Transcription Factors/genetics; Kruppel-Like Transcription Factors/therapeutic use; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Myelin P0 Protein/metabolism; S100 Calcium Binding Protein beta Subunit/metabolism; Sciatic Neuropathy/pathology; Spinal Cord/pathology; Time Factors; Transduction, Genetic

Key words

Acellular nerve allograft; Axonal regeneration; Fluorogold (FG); KLF7; Krüppel-like Factor 7 (KLF7); Peripheral nerve injury; acellular nerve allograft (ANA); adeno-associated virus 2 (AAV2); central nervous system (CNS); cholera toxin B (CTB); day (d); dorsal root ganglia (DRG); electroneurogram (ENG); glial fibrillary acidic proteins (GFAP); neurofilaments (NF); peripheral nervous system (PNS); sciatic function index (SFI); small proline-rich repeat protein 1A (SPRR1A); tyrosine kinase A (TrkA)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Sciatic Neuropathy / Kruppel-Like Transcription Factors / Allografts / Nerve Regeneration Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neurol Res Year: 2016 Type: Article Affiliation country: China

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